Yasuro Sugimoto Selected Research

Gossypol

7/2010	Induction of apoptosis by (-)-gossypol-enriched cottonseed oil in human breast cancer cells.
1/2007	Modulation of multidrug resistance gene expression in human breast cancer cells by (-)-gossypol-enriched cottonseed oil.
9/2006	Effects of serum on (-)-gossypol-suppressed growth in human prostate cancer cells.
1/2004	The inhibitory effects of gossypol on human prostate cancer cells-PC3 are associated with transforming growth factor beta1 (TGFbeta1) signal transduction pathway.
5/2002	Effects of gossypol on O2 consumption and CO2 production in human prostate cancer cells.
1/2002	The (-)-enantiomer of gossypol possesses higher anticancer potency than racemic gossypol in human breast cancer.

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Yasuro Sugimoto Research Topics

Disease

21	Breast Neoplasms (Breast Cancer) 01/2017 - 01/2002
15	Neoplasms (Cancer) 01/2017 - 11/2002
4	Prostatic Neoplasms (Prostate Cancer) 09/2006 - 05/2002
3	Lung Neoplasms (Lung Cancer) 01/2006 - 01/2002
2	Cataract (Cataracts) 05/2015 - 11/2009
2	Carcinogenesis 01/2006 - 01/2002
1	Triple Negative Breast Neoplasms 01/2017
1	Noninfiltrating Intraductal Carcinoma (DCIS) 08/2011
1	Carcinoma (Carcinomatosis) 08/2011
1	Hyperplasia 08/2011
1	Cardiovascular Diseases (Cardiovascular Disease) 08/2011
1	Neoplasm Metastasis (Metastasis) 01/2004

Drug/Important Bio-Agent (IBA)

8	Messenger RNA (mRNA)IBA 05/2015 - 01/2002
8	Estrogens (Estrogen)FDA Link 08/2011 - 11/2002
7	Aromatase (CYP19)IBA 05/2015 - 05/2005
6	GossypolIBA 07/2010 - 01/2002
5	Estradiol (Delestrogen)FDA LinkGeneric 05/2015 - 01/2002
5	Proteins (Proteins, Gene)FDA Link 06/2010 - 01/2004
4	Protein Tyrosine PhosphatasesIBA 06/2010 - 01/2002
4	Hormones (Hormone)IBA 02/2010 - 05/2005
3	Small Interfering RNA (siRNA)IBA 01/2013 - 02/2012
3	Estrogen ReceptorsIBA 08/2011 - 01/2006
3	Cottonseed Oil (Cottonseed)IBA 07/2010 - 01/2004
3	EnzymesIBA 02/2010 - 05/2005
3	Estrogen Receptor alphaIBA 08/2009 - 01/2006
3	Tamoxifen FDA LinkGeneric 08/2009 - 05/2006
3	Fibroblast Growth Factor 7 FDA Link 08/2009 - 05/2006
3	ZeranolIBA 02/2004 - 01/2002
2	Pharmaceutical PreparationsIBA 01/2017 - 02/2010
2	Green Fluorescent ProteinsIBA 07/2012 - 02/2012
2	LipidsIBA 07/2012 - 05/2010
2	Celecoxib (Celebrex)FDA Link 08/2011 - 05/2005
2	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 08/2007 - 05/2005
2	Enzyme Inhibitors (Inhibitors, Enzyme)IBA 08/2007 - 05/2005
2	Conjugated Linoleic AcidsIBA 03/2006 - 11/2005
1	Phosphotransferases (Kinase)IBA 01/2017
1	Biological ProductsIBA 01/2017
1	SulfatasesIBA 05/2015
1	Lipid NanoparticlesIBA 01/2013
1	Human Serum Albumin FDA LinkGeneric 01/2013
1	erucylphosphocholineIBA 07/2012
1	exemestane (Aromasin)FDA Link 08/2011
1	Progesterone FDA LinkGeneric 08/2011
1	Class 5 Receptor-Like Protein Tyrosine PhosphatasesIBA 06/2010
1	Aromatase InhibitorsIBA 05/2010
1	Transferrin (beta 2 Transferrin)IBA 05/2010
1	Capsules (Microcapsules)IBA 11/2009
1	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 08/2009
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2007
1	Dextrans (Dextran)FDA Link 09/2006
1	Bovine Serum AlbuminIBA 09/2006
1	Blood Proteins (Serum Proteins)IBA 09/2006
1	Charcoal (Charbon)IBA 09/2006
1	Peptides (Polypeptides)IBA 05/2006
1	Progesterone Receptors (Progesterone Receptor)IBA 05/2006
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 05/2006
1	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 03/2006
1	Dinoprostone (PGE2)FDA Link 03/2006
1	Linoleic Acid (Linoleate)IBA 03/2006
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 11/2005
1	Piroxicam (Feldene)FDA LinkGeneric 05/2005
1	Niflumic AcidIBA 05/2005
1	Indomethacin (Indometacin)FDA LinkGeneric 05/2005
1	Ibuprofen (Motrin)FDA LinkGeneric 05/2005
1	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 05/2005
1	1- ((4- methylsulfonyl)phenyl)- 3- trifluoromethyl- 5- (4- fluorophenyl)pyrazoleIBA 05/2005
1	N- (2- cyclohexyloxy- 4- nitrophenyl)methanesulfonamideIBA 05/2005
1	nimesulide (Aulin)IBA 05/2005
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 02/2004
1	Tyrosine (L-Tyrosine)FDA Link 02/2004
1	AgarIBA 02/2004
1	Cyclin D1IBA 01/2004
1	AndrogensIBA 01/2004
1	ThymidineIBA 01/2004
1	Transforming Growth Factor beta1 (TGF beta 1)IBA 01/2004

Therapy/Procedure

5	Therapeutics 01/2017 - 05/2005
3	Mammaplasty (Breast Reconstruction) 01/2006 - 01/2002
1	Drug Therapy (Chemotherapy) 01/2007